Book through our site
—up to 10% cheaper
than Booking.com
Check rooms and rates
From91US$ /night
Check-in
12Dec2025Select date
Check-out
13Dec2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

21 Via Di Mezzo, Florence, Italy, 50121
-
Close to the Cathedral of Santa Maria del Fiore
Perfect
9.6
/10

Location

Affittacamere Medusa is situated in a central area of Florence, within walking distance to key attractions such as the Accademia Gallery and San Lorenzo Market. The hotel is located approximately a 10-minute walk from Santa Maria Novella Train Station, making travel to and from the property convenient. Its position near public transportation allows easy access to explore the city's renowned sights.

Rooms

The hotel offers a variety of room types, including classic doubles and triple rooms. Each room provides essential amenities such as air conditioning and satellite TV to ensure a comfortable stay. Selected rooms boast en-suite bathrooms, contributing to guest privacy.

Dining

While Affittacamere Medusa does not feature on-site dining, it is located near several local cafes and restaurants that serve traditional Florentine cuisine. Guests can explore nearby eateries offering breakfast, lunch, and dinner options within a short walk. The hotel staff can recommend local favorites to enhance the culinary experience.

Wellness

The hotel does not have a dedicated wellness facility; however, its location allows access to wellness spas and fitness centers around Florence. Guests may choose to enjoy a local spa treatment or fitness class during their stay. The nearby parks also offer options for outdoor exercise.

Accessibility

Affittacamere Medusa provides easy check-in and check-out services, ensuring a seamless experience for guests. Its central location supports accessibility to various public transport options, enhancing travel convenience. The hotel's layout is friendly for visitors needing assistance.

Highlights

Location: central area of Florence

Rooms: classic doubles and triple rooms

Dining: traditional Florentine cuisine nearby

Accessibility: easy check-in and check-out services

“This adults-only property, located a short walk from the city center, stands out for its personalized service and modern, well-maintained rooms. Its location in the San Marco-Santissima Annunziata district provides convenient access to Florence's attractions while maintaining a quieter atmosphere. I especially note the emphasis on creating a welcoming and helpful environment for guests, making it a solid choice for couples or solo travelers.”
Hotel logo
James DavidEditor-in-Chief at Cheaphotels
View all

Select your room type

The hotel provides a selection of rooms—doubles, family rooms, and suites—with perks like free cancellation, breakfast options, and great value deals
Standard Double Suite
2 persons
48 m² 
1 King-size bed
Shower
Heating
Large Double Room
2 persons
25 m² 
1 King-size bed
Shower
Heating
Double or Twin Room Private Bathroom
2 persons
21 m² 
1 King-size bed
Shower
Heating
Double or Twin Room Garden View
2 persons
19 m² 
1 King-size bed
Shower
Heating
Click button to see more rooms
Show all rooms
Show all roomsLess

Room rates & availability calendar

See the best prices and book your dates today!

Amenities & services

Real traveler stories and honest reviews—no glossy ads, just authentic feedback to guide your booking

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • No pets allowed
  • Security
  • Adults only
  • Luggage storage
  • Key access

Services

  • Valet parking

Room features

  • Air conditioning
  • Heating

Bathroom

  • Free toiletries
Show more

Location

21 Via Di Mezzo, Florence, Italy, 50121
Map view
21 Via Di Mezzo, Florence, Italy, 50121
Nearby
Museum
Casa Buonarroti
550 m
Synagogue
Sinagoga Synagogue and Jewish Museum
370 m
Restaurants
Hangar
410 m
Via Dei Pepi 43
College Firenze
240 m
Via Pietrapiana 21/R
La Ghiotta
210 m
Via Pietrapiana 7/R
I ragazzi di sipario
420 m
Via Dell'Ulivo 6r All'interno Dello Spazio Alfieri
Panificio Brunori
630 m
Borgo Pinti 16 R
Iyoiyo
550 m
Borgo Pinti 25/R
Mesopotamia
530 m
Piazza Gaetano Salvemini 14
Explore Florence
Local Highlights
Top Attractions
Activities
Dining
Entertainment
Gallerie Degli Uffizi
Gallerie Degli Uffizi
16 minutes' walk
Art museum housing masterpieces by Botticelli and Michelangelo. Offers guided tours and free admission on the first Sunday of each month.
Ponte Vecchio
Ponte Vecchio
19 minutes' walk
Iconic medieval bridge lined with jewelry shops. An excellent spot for photos and offers views of the river and surrounding architecture.
Piazza del Duomo
Piazza del Duomo
13 minutes' walk
Home to Florence Cathedral, famous for its stunning dome. Visitors can access the cathedral and its museum for a small fee.
Basilica of Santa Croce in Florence
Basilica of Santa Croce in Florence
10 minutes' walk
Final resting place of many renowned Italians. Known for its beautiful frescoes and the surrounding square with artisan shops.
Biking through Florence
5 minutes' walk
Rent bicycles from nearby shops. Visit various attractions at your own pace while enjoying Florence's stunning streets and parks.
Relax in Giardino Bardini
25 minutes' walk
A serene garden with beautiful views and art. Ideal for a leisurely stroll or relaxing amidst nature with seasonal blooms.
Hangar
Hangar
5 minutes' walk
Contemporary eatery offering Italian and Mediterranean dishes in a trendy setting. Reservations recommended, with vegetarian options available.
College Firenze
College Firenze
3 minutes' walk
Casual dining spot serving pizza and pasta. Known for its lively atmosphere and quick service, making it perfect for families.
Caffè Gilli
10 minutes' walk
Historic café with a vibrant atmosphere. Ideal for live music events, serving coffee and pastries. A great spot for families too.
Teatro della Pergola
20 minutes' walk
One of Italy's oldest theaters featuring a variety of performances. Check the schedule for shows ranging from classical to contemporary.
Getting around town
City Centre
Florence10 min  ·  800 m
Airports
Peretola Airport (FLR)14 min  ·  8.9 km
Pisa International Airport - Galileo Galilei (PSA)126 min  ·  83.8 km
Train
Campo di Marte Station15 min  ·  1.2 km
Bus
Bus stop3 min  ·  200 m
Looking for early-bird discounts?
Get special discounted rates today!
Check Rates
Property information and rules
Check-in
from 15:00-18:00
Check-out
until 10 am
Internet
is available in for free.
Pets
Pets are not allowed.
FAQs
About Affittacamere Medusa
What is the check-in and check-out policy for Affittacamere Medusa?
Check-in is at 15:00 and check-out is by 10:00.
Is parking available at Affittacamere Medusa?
Public parking is available nearby for 30 EUR per day, and reservation is needed.
What room amenities are provided at Affittacamere Medusa?
Rooms include air conditioning, a private bathroom with free toiletries, a desk, and bed linen.
What dining options are available near Affittacamere Medusa?
Nearby restaurants include La Pentola dell'Oro (0.5 km), Ristorante Pentola Dell'Oro (0.5 km), and Universo Vegano (0.5 km).
What attractions are located close to Affittacamere Medusa?
Nearby attractions include the Accademia Gallery (less than 1 km), Piazzo del Duomo (800 m), and Uffizi Gallery (1 km).
What is the distance from Affittacamere Medusa to Florence Airport?
Florence Airport is located 10 km from the property.
Are there any adult-only policies at Affittacamere Medusa?
Affittacamere Medusa is an adults-only hotel.
Is Wi-Fi available at Affittacamere Medusa?
Free Wi-Fi is available throughout the property.
Is there an option for luggage storage at Affittacamere Medusa?
Luggage storage service is available for guests.

Next best alternative

Consider them for your next trip.
Check-in
12Dec2025Select date
Check-out
13Dec2025Select date
Rooms and Guests2 Guests, 1 Room
Need more options?
Check Top hotels near Affittacamere Medusa
Palazzo Dei Ciompi Suites Florence Nearby photo
Mobile-only price

Palazzo Dei Ciompi Suites Florence

7.2
Very good1937 reviews
103m from property
USD 66USD 59
per night
Hotel Arizona Florence Exterior photo
Mobile-only price

Hotel Arizona Florence

7.0
Very good1304 reviews
105m from property
USD 53USD 47
per night
Hotel Bodoni Florence Fast Food photo
Mobile-only price

Hotel Bodoni Florence

7.7
Very good6158 reviews
111m from property
USD 66USD 59
per night